All active ingredients present in food supplements are interesting and have their specific use. At rare times, the value of some supplement is underestimated even by researchers. If you happen to be familiar with the research on Agmatine, then you may agree that the latter is such a supplement. In fact, Agmatine sulfate is one of those special substances that many may not have heard of.

 

Known for more than 100 years

In 1910 Agmatine was discovered by Nobel prize laureate Albrecht Kossel. The body produces it by conversion of the amino acid L-arginine. Agmatine abounds especially in the intestines. The intestinal flora is an important factor in agmatine production. In addition to the body’s production, we obtain agmatine from our diet. Plant foods, fish and meat, for example, contain varying concentrations of agmatine.

 

Magic shotgun

From the intestines Agmatine is distributed throughout the body, including the nervous system. Its physiological properties are unique, because unlike for example B vitamins and antioxidants, they have a very broad metablic scope.

The effects project onto multiple biochemical pathways simultaneously. Agmatine is undoubtedly physiologically potent. Influencing multiple pathways of biochemistry fits a complex system like the human body like a glove.

Agmatine acts as a “magic shotgun” capable of supporting numerous complex systems simultaneously.

Nootropic, ergogenic and nutraceutical

The working mechanisms of Agmatine in part resemble those of L-Arginine (the parent molecule) but the former are much more extensive and intensive. Among other uses, Agmatine is known as a nootropic, ergogenic and nutraceutical supplement. As ergogenic agent it has become very popular in the strength training world a few years back given its association with nitric oxide (NO). For the more health-oriented consumer its uses as nootropic and nutraceutical may be more interesting. The latter uses refer more to its effects on the neurotransmitter system and polyamine metabolism.

 

Polyamines

Polyamines are basic molecules that are found throughout the body. They are involved in various vital cellular processes such as associated with energy metabolism. The only polyamines produced by the human body are putrescine, spermidine and spermine. In recent years there has been an increase of interest in polyamines by the scientific community because they are important for health maintenance. The production of polyamines decreases with age and thus, eating polyamine-rich food, such as through plants or supplementation, seems to gain in importance with age.

 

R-Alpha Lipoic Acid and Agmatine

The combination of R-Alpha Lipoic Acid, Biotin and Agmatine is widely used because of the natural synergy of these compounds. All three substances have a specific interaction with the nervous system and various dosing regimes may be recommended to cater to individual needs.

 

Agmatine is safe

Agmatine is a safe nutraceutical. Long-term safety data are available and no serious side effects have been reported among the hundreds of thousands, if not millions, of users. The recommended daily intake ranges from 1000 mg to 2500 mg.

 

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